Hispanic Population Studies

Hispanic Population Studies

The John P. Hussman Institute for Human Genomics (HIHG) is dedicated to addressing health disparities in genomic research. Results from these studies will translate into better diagnoses and eventual treatments for a broader community of people.

Two separate projects will focus on Alzheimer’s Disease (AD) within Hispanic populations.

The first project, titled “Genetic Epidemiology of Early-Onset Alzheimer’s Disease in Caribbean Hispanics and non-Hispanic Whites” is headed by principal investigator Dr. Gary Beecham, Director of the Division of Research Informatics in the Center for Genetic Epidemiology and Statistical Genetics at the HIHG, along with co-principal investigator, Dr. Christiane Reitz of Columbia University. For this project, researchers will form a collection of Hispanic/Latino subjects with and without AD. The team will perform whole-genome sequencing of families with multiple generations affected by AD to identify novel AD variation in Hispanics/Latinos and to generalize existing AD genetic discoveries to this underrepresented population.

The second project is the Puerto Rican Alzheimer’s Disease Initiative (PRADI) which primarily focuses on the genomic characterization of AD risk within the Puerto Rican population.