Non-Mendelian Inheritance

   Lesson 1: Triplet Repeat Disorders
   Lesson 2: Genomic Imprinting
   Lesson 3: Mosaicism
   Lesson 4: Mitochondrial Mutations

This course covers the pattern of non-Mendelian inheritance. After completing it, you will have a basic understanding of:

  • Features of triplet repeat disorders and their inheritance
  • Genomic imprinting and uniparental disomy and their clinical consequences
  • Germline and somatic mosaicism
  • Mitochondrial DNA mutations, their inheritance, and possible clinical symptoms

Instructions to Users
Links to supplemental clinical information are included in some lessons and are indicated by the underlined words. Words appearing in bold are keywords you may enter in the Search field. Use the arrow buttons on each lesson page to scroll for additional text.

Developed by the Center for Human Genetics, Duke University Medical Center and maintained by the John P. Hussman Institute for Human Genomics, University of Miami, with support from National Human Genome Research Institute (HG00026), and the Bureau of Health Professions in the Department of Health and Human Services (1D49HP100000)