Core Services : Histopathology Core

Histopathology Core

Contact: Juan Young, Ph.D.

Histopathology is the diagnosis and study of disease by interpretation of cells and tissue samples — a crucial step in the cultivation and research of genetic material. The Histopatholgy Core at the John P. Hussman Institute for Human Genomics performs routine histological staining like H&E, Bielschowsky silver stain and immunohistochemistry of β-Amyloid, α-Synuclein and Tau of brain tissue for the diagnosis of diseases like Alzheimer’s and Parkinson’s disease. The Histopathology Core also provides help and guide for tissue preparation, histological staining and using of histological instruments for different projects.

Our equipment includes:
• Leica RM2125 rotary microtome: for cutting FFPE tissue blocks.
• Leica CM1850 UV cryostat: for cutting frozen tissue.
• Leica VT1200 Vibrotome: for cutting tissue for confocal microscopy and electron microscopy.
• Leica EM UC6 ultramicrotome: for cutting ultrathin sections for electron microscopical study of brain and other tissue.