News : 2017 : March

Cancer Genomics: From Etiology to Precision Medicine

Human Genetics and Genomics Seminar Series

“Cancer Genomics: From Etiology to Precision Medicine”

Jennifer Hu, Ph.D.
Department of Biochemistry & Molecular Biology
Department of Public Health Sciences,
Division of Epidemiology & Population Health Sciences

DATE: Monday, March 20, 2017

TIME: 4:00p – 5:00p

Biomedical Research Building (BRB) John P. Hussman Institute
1501 NW 10th Avenue
3rd/4th Floor Atrium

Research Summary:

Dr. Hu’s research mainly focuses on the molecular and genetic mechanisms of breast cancer risk and survival disparities and implication of DNA damage and repair in precision medicine. The pioneer research from her laboratory and collaborative effort that has significant impact on the cancer research field include: (1) deficient DNA repair and elevated DNA damage in human breast and prostate cancer risk; (2) racial/ethnic specific polygenic models of DNA repair in human cancer risk and tumor TP53 mutations; (3) functional implication of DNA repair genotypes in human cancer risk and targeted therapies; (4) gene-diet interactions in human colon and breast cancer risk; (5) genome-wide association studies of novel breast cancer and ER-negative breast cancer susceptibility loci in women of African ancestry; and (6) prediction models for radiation sensitivity in breast cancer treatment responses.

She is the course director for Molecular and Genetic Epidemiology and Cancer Epidemiology. Her research program has been continuously funded for more than 20 years with peer-reviewed grants from NIH/NCI/ACS/DOD/FLDOH since 1992. Her scientific expertise includes basic laboratory research in DNA damage/repair, molecular and genetic epidemiology, genomic prediction models of survival, precision medicine, and cancer health disparities. With her diverse research background and strong commitment in training/education, she has successfully mentored a number of young scientists with outstanding career development. She has served on more than 50 NIH/NCI/DOD study sections; became a member of the NCI subcommittee F for T32/R25 training grants in 2013.