Our Studies : Dementia with Lewy Bodies Research (DLB)

Dementia with Lewy Bodies (DLB)

Approximately 5% of all dementia patients present with Dementia with Lewy bodies (DLB), affecting a total of 2% of the general population above 65 years of age. DLB is often referred to as an AD related dementia and shows overlap with both Alzheimer disease (AD) and Parkinson disease (PD) on a clinical, pathological and genetic level.

Very limited information is known on underlying biological processes explaining this disease. Genetic analyses in case-control cohorts and large families with a family history for disease have been instrumental in understanding biological processes for many other diseases. So far, however, genetic research in DLB has been very limited and mostly focused on analyses in non-Hispanic white cohorts.

The HIHG team led by Drs. Nuytemans, Pericak-Vance and Vance are committed to extend the DLB research beyond the overlap with AD and PD and into diverse populations to identify novel variants and understand genetic contributions to DLB across populations.

For more information, or to participate in our Dementia with Lewy Bodiues study, please contact our study coordinator:

Antonella Grana