The Pedigree Disequilibrium Test (PDT) analysis program allows the user to test for linkage and association in general pedigree data. In addition to allele- and genotype-specific analysis of individual markers. PDT version 5.1 adds the ability to perform genotype-specific analysis over marker.
PDT version 6.0 does not have the ability to perform -specific analysis over marker sets. It is significantly faster than PDT 5.1 and has no restriction on the number of markers or pedigrees. Email firstname.lastname@example.org if you have any problems downloading. References:
Eden R. Martin, S. Monks, L. Warren, N. Kaplan (2000) A Test for Linkage and Association in General Pedigrees:The Pedigree Disequilibrium Test. Am. J. Hum. Genet. 67:146-154, 2000
Letter to the Editor: Correcting for a Potential Bias in the Pedigree Disequilibrium Test. Am. J. Hum. Genet. 68:1065-1067, 2001